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We apply MATSim (Multi-Agent Transport Simulation) framework for simulating traffic and transportation in the Tel-Aviv Metropolitan Area. MATSim is highly flexible agent-based simulation environment capable of high-resolution representation of travelers’ population and transportation network. We calibrate and validate MATSim model for the Tel Aviv metropolitan area based on traffic counts and Google data of traffic speed. See MATSim application in Tel-Aviv Metropolitan Area on the youtube.We apply MATSim in several projects, including the influence of Rapid Bus Lines on urban public transport, and introduction of the Shared Autonomous Vehicles (SAV) and a new transportation mode. The goal of the latter study is to investigate the society adoption of the SAV and co-adaptation of the travelers and transportation system with the increase in the SAV use. The research combines a novel methodology of Game-Based Modeling with stated preferences study and MATSim-based simulation modeling. We test different scenarios of the AV adoption in the metropolitan areas of Beer-Sheba and Tel -Aviv.